Dapagliflozin impedes endothelial cell senescence by activating the SIRT1 signaling pathway in type 2 diabetes

BACKGROUND: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) clinically reduce atherosclerosis and lower blood pressure. However, their impact on endothelial dysfunction in type 2 diabetes (T2D) remains unclear. In this study, we investigated the protective effect and underlying mechanism of the S...

Descripción completa

Detalles Bibliográficos
Autores principales: Tai, Shi, Zhou, Ying, Fu, Liyao, Ding, Huiqing, Zhou, Yuying, Yin, Zhiyi, Yang, Rukai, Liu, Zhenjiang, Zhou, Shenghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469571/
https://www.ncbi.nlm.nih.gov/pubmed/37664712
http://dx.doi.org/10.1016/j.heliyon.2023.e19152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469571/
https://www.ncbi.nlm.nih.gov/pubmed/37664712
http://dx.doi.org/10.1016/j.heliyon.2023.e19152

Ejemplares similares