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Dapagliflozin impedes endothelial cell senescence by activating the SIRT1 signaling pathway in type 2 diabetes

BACKGROUND: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) clinically reduce atherosclerosis and lower blood pressure. However, their impact on endothelial dysfunction in type 2 diabetes (T2D) remains unclear. In this study, we investigated the protective effect and underlying mechanism of the S...

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Detalles Bibliográficos
Autores principales:	Tai, Shi, Zhou, Ying, Fu, Liyao, Ding, Huiqing, Zhou, Yuying, Yin, Zhiyi, Yang, Rukai, Liu, Zhenjiang, Zhou, Shenghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469571/ https://www.ncbi.nlm.nih.gov/pubmed/37664712 http://dx.doi.org/10.1016/j.heliyon.2023.e19152

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