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Molecular basis of the glycosomal targeting of PEX11 and its mislocalization to mitochondrion in trypanosomes

PEX19 binding sites are essential parts of the targeting signals of peroxisomal membrane proteins (mPTS). In this study, we characterized PEX19 binding sites of PEX11, the most abundant peroxisomal and glycosomal membrane protein from Trypanosoma brucei and Saccharomyces cerevisiae. TbPEX11 contains...

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Detalles Bibliográficos
Autores principales: Krishna, Chethan K., Schmidt, Nadine, Tippler, Bettina G., Schliebs, Wolfgang, Jung, Martin, Winklhofer, Konstanze F., Erdmann, Ralf, Kalel, Vishal C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469627/
https://www.ncbi.nlm.nih.gov/pubmed/37664461
http://dx.doi.org/10.3389/fcell.2023.1213761