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Mismatch Repair Deficient (dMMR) Colorectal Carcinoma in a Pakistani Cohort: Association With Clinical and Pathological Parameters

Introduction Microsatellite instability (MSI) is an important pathway in colorectal carcinoma (CRC) pathogenesis. MSI occurs due to mutations in mismatch repair (MMR) genes that include MutL protein homolog 1 (MLH1), postmeiotic segregation increased 2 (PMS2), MutS homolog 2 (MSH2), and MutS homolog...

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Detalles Bibliográficos
Autores principales: Hashmi, Atif A, Bukhari, Ummara, Rizwan, Ramish, Faisal, Faiza, Kumar, Ravi, Malik, Umair Arshad, Zia, Shamail, Khan, Abdur Rahim, Sham, Sunder, Irfan, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469632/
https://www.ncbi.nlm.nih.gov/pubmed/37664303
http://dx.doi.org/10.7759/cureus.42781