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Identification and validation of Birc5 as a novel activated cell cycle program biomarker associated with infiltration of immunosuppressive myeloid‐derived suppressor cells in hepatocellular carcinoma

BACKGROUND: Preclinical studies and clinical trials have demonstrated that tumor‐intrinsic activation of the cell cycle program impedes anticancer immunotherapy. Identification of cell cycle‐related biomarkers may provide novel therapeutic targets to augment the efficacy of immunotherapy in hepatoce...

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Detalles Bibliográficos
Autores principales: Liu, Yun, Chen, Xi, Luo, Wenwu, Zhao, Yufei, Nashan, Björn, Huang, Lei, Yuan, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469657/
https://www.ncbi.nlm.nih.gov/pubmed/37326143
http://dx.doi.org/10.1002/cam4.6271