Pre-clinical delivery of gene therapy products to the cerebrospinal fluid: challenges and considerations for clinical translation

While the majority of gene therapy studies in neurological indications have focused on direct gene transfer to the central nervous system (CNS), there is growing interest in the delivery of therapeutics using the cerebrospinal fluid (CSF) as a conduit. Historically, direct CNS routes-of-administrati...

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Detalles Bibliográficos
Autores principales: Salegio, Ernesto A., Hancock, Kelli, Korszen, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469667/
https://www.ncbi.nlm.nih.gov/pubmed/37664241
http://dx.doi.org/10.3389/fnmol.2023.1248271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469667/
https://www.ncbi.nlm.nih.gov/pubmed/37664241
http://dx.doi.org/10.3389/fnmol.2023.1248271

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