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Pre-clinical delivery of gene therapy products to the cerebrospinal fluid: challenges and considerations for clinical translation
While the majority of gene therapy studies in neurological indications have focused on direct gene transfer to the central nervous system (CNS), there is growing interest in the delivery of therapeutics using the cerebrospinal fluid (CSF) as a conduit. Historically, direct CNS routes-of-administrati...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469667/ https://www.ncbi.nlm.nih.gov/pubmed/37664241 http://dx.doi.org/10.3389/fnmol.2023.1248271 |