A phosphorylation-deficient mutant of Sik3, a homolog of Sleepy, alters circadian sleep regulation by PDF neurons in Drosophila

Sleep behavior has been observed from non-vertebrates to humans. Sleepy mutation in mice resulted in a notable increase in sleep and was identified as an exon-skipping mutation of the salt-inducible kinase 3 (Sik3) gene, conserved among animals. The skipped exon includes a serine residue that is pho...

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Detalles Bibliográficos
Autores principales: Kobayashi, Riho, Nakane, Shin, Tomita, Jun, Funato, Hiromasa, Yanagisawa, Masashi, Kume, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469759/
https://www.ncbi.nlm.nih.gov/pubmed/37662102
http://dx.doi.org/10.3389/fnins.2023.1181555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469759/
https://www.ncbi.nlm.nih.gov/pubmed/37662102
http://dx.doi.org/10.3389/fnins.2023.1181555

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