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Prognostic value of Lynch syndrome, BRAF(V600E) , and RAS mutational status in dMMR/MSI‐H metastatic colorectal cancer in a pooled analysis of Dutch and French cohorts

BACKGROUND: Current knowledge on prognostic biomarkers (especially BRAF ( V600E )/RAS mutations) in metastatic colorectal cancer (mCRC) is mainly based on mCRC patients with proficient mismatch repair (pMMR) tumors. It is uncertain whether these biomarkers have the same prognostic value in mCRC pati...

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Detalles Bibliográficos
Autores principales: Zwart, Koen, van der Baan, Frederieke H., Cohen, Romain, Aparicio, Thomas, de la Fouchardiére, Christelle, Lecomte, Thierry, Punt, Cornelis J. A., Sefrioui, David, Verheijden, Rik J., Vink, Geraldine R., Wensink, G. Emerens, Zaanan, Aziz, Koopman, Miriam, Tougeron, David, Roodhart, Jeanine M. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469760/
https://www.ncbi.nlm.nih.gov/pubmed/37326121
http://dx.doi.org/10.1002/cam4.6223