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Improved prediction of MHC-peptide binding using protein language models

Major histocompatibility complex Class I (MHC-I) molecules bind to peptides derived from intracellular antigens and present them on the surface of cells, allowing the immune system (T cells) to detect them. Elucidating the process of this presentation is essential for regulation and potential manipu...

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Detalles Bibliográficos
Autores principales: Hashemi, Nasser, Hao, Boran, Ignatov, Mikhail, Paschalidis, Ioannis Ch., Vakili, Pirooz, Vajda, Sandor, Kozakov, Dima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469926/
https://www.ncbi.nlm.nih.gov/pubmed/37663788
http://dx.doi.org/10.3389/fbinf.2023.1207380