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Association of TP53 rs1042522 G > C, MDM2 rs2279744 T > G, and miR-34b/c rs4938723 T > C polymorphisms with aneuploidy pregnancy susceptibility

BACKGROUND: Aneuploidy pregnancy is a severe major birth defect and causes about 50% spontaneous miscarriages with unknown etiology. To date, only a few epidemiological studies with small sample sizes have investigated the risk factors for aneuploidy pregnancy. TP53, MDM2, and miR-34b/c genes are im...

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Detalles Bibliográficos
Autores principales: Chan, Ying, Xu, Weiming, Feng, Yan, Zhang, Yan, Li, Suyun, Geng, Zibiao, Liu, Zhijiao, Zhao, Qingfen, Zhang, Jinman, Zhu, Baosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469955/
https://www.ncbi.nlm.nih.gov/pubmed/37648962
http://dx.doi.org/10.1186/s12884-023-05945-3