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Immunopathogenesis in Trypanosoma cruzi infection: a role for suppressed macrophages and apoptotic cells

During Trypanosoma cruzi infection, macrophages phagocytose parasites and remove apoptotic cells through efferocytosis. While macrophage 1 (M1) produces proinflammatory cytokines and NO and fights infection, M2 macrophages are permissive host cells that express arginase 1 and play a role in tissue r...

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Detalles Bibliográficos
Autores principales: Vellozo, Natália S., Matos-Silva, Thayane C., Lopes, Marcela F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469960/
https://www.ncbi.nlm.nih.gov/pubmed/37662946
http://dx.doi.org/10.3389/fimmu.2023.1244071