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Acidosis attenuates CPT-I-supported bioenergetics as a potential mechanism limiting lipid oxidation

Fuel interactions in contracting muscle represent a complex interplay between enzymes regulating carbohydrate and fatty acid catabolism, converging in the mitochondrial matrix. While increasing exercise intensity promotes carbohydrate use at the expense of fatty acid oxidation, the mechanisms underl...

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Detalles Bibliográficos
Autores principales: Frangos, Sara M., DesOrmeaux, Geneviève J., Holloway, Graham P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469998/
https://www.ncbi.nlm.nih.gov/pubmed/37482278
http://dx.doi.org/10.1016/j.jbc.2023.105079