Cargando…

Lipoylation is dependent on the ferredoxin FDX1 and dispensable under hypoxia in human cells

Iron–sulfur clusters (ISC) are essential cofactors that participate in electron transfer, environmental sensing, and catalysis. Amongst the most ancient ISC-containing proteins are the ferredoxin (FDX) family of electron carriers. Humans have two FDXs- FDX1 and FDX2, both of which are localized to m...

Descripción completa

Detalles Bibliográficos
Autores principales: Joshi, Pallavi R., Sadre, Shayan, Guo, Xiaoyan A., McCoy, Jason G., Mootha, Vamsi K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470009/
https://www.ncbi.nlm.nih.gov/pubmed/37481209
http://dx.doi.org/10.1016/j.jbc.2023.105075