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Lipoylation is dependent on the ferredoxin FDX1 and dispensable under hypoxia in human cells
Iron–sulfur clusters (ISC) are essential cofactors that participate in electron transfer, environmental sensing, and catalysis. Amongst the most ancient ISC-containing proteins are the ferredoxin (FDX) family of electron carriers. Humans have two FDXs- FDX1 and FDX2, both of which are localized to m...
Autores principales: | Joshi, Pallavi R., Sadre, Shayan, Guo, Xiaoyan A., McCoy, Jason G., Mootha, Vamsi K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470009/ https://www.ncbi.nlm.nih.gov/pubmed/37481209 http://dx.doi.org/10.1016/j.jbc.2023.105075 |
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