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PARP14 is a writer, reader, and eraser of mono-ADP-ribosylation

PARP14/BAL2 is a large multidomain enzyme involved in signaling pathways with relevance to cancer, inflammation, and infection. Inhibition of its mono-ADP-ribosylating PARP homology domain and its three ADP-ribosyl binding macro domains has been regarded as a potential means of therapeutic intervent...

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Detalles Bibliográficos
Autores principales: Torretta, Archimede, Chatzicharalampous, Constantinos, Ebenwaldner, Carmen, Schüler, Herwig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470015/
https://www.ncbi.nlm.nih.gov/pubmed/37507011
http://dx.doi.org/10.1016/j.jbc.2023.105096