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Regulation of tumor immunity and immunotherapy by the tumor collagen extracellular matrix

It has been known for decades that the tumor extracellular matrix (ECM) is dysfunctional leading to loss of tissue architecture and promotion of tumor growth. The altered ECM and tumor fibrogenesis leads to tissue stiffness that act as a physical barrier to immune cell infiltration into the tumor mi...

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Detalles Bibliográficos
Autores principales: Flies, Dallas B., Langermann, Solomon, Jensen, Christina, Karsdal, Morten A., Willumsen, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470046/
https://www.ncbi.nlm.nih.gov/pubmed/37662958
http://dx.doi.org/10.3389/fimmu.2023.1199513