Cargando…
Regulation of tumor immunity and immunotherapy by the tumor collagen extracellular matrix
It has been known for decades that the tumor extracellular matrix (ECM) is dysfunctional leading to loss of tissue architecture and promotion of tumor growth. The altered ECM and tumor fibrogenesis leads to tissue stiffness that act as a physical barrier to immune cell infiltration into the tumor mi...
Autores principales: | Flies, Dallas B., Langermann, Solomon, Jensen, Christina, Karsdal, Morten A., Willumsen, Nicholas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470046/ https://www.ncbi.nlm.nih.gov/pubmed/37662958 http://dx.doi.org/10.3389/fimmu.2023.1199513 |
Ejemplares similares
-
Serological assessment of collagen fragments and tumor fibrosis may guide immune checkpoint inhibitor therapy
por: Jensen, Christina, et al.
Publicado: (2021) -
Cancer immunotherapy by NC410, a LAIR-2 Fc protein blocking human LAIR-collagen interaction
por: Ramos, M Ines Pascoal, et al.
Publicado: (2021) -
Age-related collagen turnover of the interstitial matrix and basement membrane: Implications of age- and sex-dependent remodeling of the extracellular matrix
por: Kehlet, Stephanie N., et al.
Publicado: (2018) -
Non-invasive biomarkers derived from the extracellular matrix associate with response to immune checkpoint blockade (anti-CTLA-4) in metastatic melanoma patients
por: Jensen, Christina, et al.
Publicado: (2018) -
Matrix Metalloprotease Generated Fragments of Type VI Collagen Have Serum Biomarker Potential in Cancer – A Proof of Concept Study
por: Willumsen, Nicholas, et al.
Publicado: (2019)