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Diverse p120RasGAP interactions with doubly phosphorylated partners EphB4, p190RhoGAP, and Dok1

RasGAP (p120RasGAP), the founding member of the GTPase-activating protein (GAP) family, is one of only nine human proteins to contain two SH2 domains and is essential for proper vascular development. Despite its importance, its interactions with key binding partners remains unclear. In this study we...

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Detalles Bibliográficos
Autores principales: Vish, Kimberly J., Stiegler, Amy L., Boggon, Titus J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470053/
https://www.ncbi.nlm.nih.gov/pubmed/37507023
http://dx.doi.org/10.1016/j.jbc.2023.105098