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α-Synuclein colocalizes with AP180 and affects the size of clathrin lattices

α-Synuclein and family members β- and γ-synuclein are presynaptic proteins that sense and generate membrane curvature, properties important for synaptic vesicle (SV) cycling. αβγ-synuclein triple knockout neurons exhibit SV endocytosis deficits. Here, we investigated if α-synuclein affects clathrin...

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Detalles Bibliográficos
Autores principales: Vargas, Karina J., Colosi, P.L., Girardi, Eric, Park, Jae-Min, Harmon, Leah E., Chandra, Sreeganga S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470054/
https://www.ncbi.nlm.nih.gov/pubmed/37516240
http://dx.doi.org/10.1016/j.jbc.2023.105091