Cargando…

α-Synuclein colocalizes with AP180 and affects the size of clathrin lattices

α-Synuclein and family members β- and γ-synuclein are presynaptic proteins that sense and generate membrane curvature, properties important for synaptic vesicle (SV) cycling. αβγ-synuclein triple knockout neurons exhibit SV endocytosis deficits. Here, we investigated if α-synuclein affects clathrin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vargas, Karina J., Colosi, P.L., Girardi, Eric, Park, Jae-Min, Harmon, Leah E., Chandra, Sreeganga S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470054/ https://www.ncbi.nlm.nih.gov/pubmed/37516240 http://dx.doi.org/10.1016/j.jbc.2023.105091

Ejemplares similares

The Sybtraps: Control of Synaptobrevin Traffic by Synaptophysin, α-Synuclein and AP-180
por: Gordon, Sarah L, et al.
Publicado: (2014)

The Biochemical Properties and Functions of CALM and AP180 in Clathrin Mediated Endocytosis
por: Moshkanbaryans, Lia, et al.
Publicado: (2014)

AP180 Couples Protein Retrieval to Clathrin-Mediated Endocytosis of Synaptic Vesicles
por: Vanlandingham, Phillip A, et al.
Publicado: (2014)

The ∼16 kDa C-Terminal Sequence of Clathrin Assembly Protein AP180 Is Essential for Efficient Clathrin Binding
por: Chan, Ling-Shan, et al.
Publicado: (2014)

A Novel Sequence in AP180 and CALM Promotes Efficient Clathrin Binding and Assembly
por: Moshkanbaryans, Lia, et al.
Publicado: (2016)

Docosahexaenoic acid-containing phosphatidic acid interacts with clathrin coat assembly protein AP180 and regulates its interaction with clathrin
por: Hoshino, Fumi, et al.
Publicado: (2022)

Actin polymerization promotes invagination of flat clathrin-coated lattices in mammalian cells by pushing at lattice edges
por: Yang, Changsong, et al.
Publicado: (2022)

Association and Colocalization of Eps15 with Adaptor Protein-2 and Clathrin
por: van Delft, Sanne, et al.
Publicado: (1997)

Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles
por: Kovtun, Oleksiy, et al.
Publicado: (2020)

Roles of AP-2 in Clathrin-Mediated Endocytosis
por: Boucrot, Emmanuel, et al.
Publicado: (2010)

Impacts of increased α-synuclein on clathrin-mediated endocytosis at synapses: implications for neurodegenerative diseases
por: Medeiros, Audrey T., et al.
Publicado: (2018)

Effects of cytoplasmic acidification on clathrin lattice morphology
Publicado: (1989)

Clathrin and clathrin adaptor AP-1 control apical trafficking of megalin in the biosynthetic and recycling routes
por: Gravotta, Diego, et al.
Publicado: (2019)

Differential requirements for AP-2 in clathrin-mediated endocytosis
por: Conner, Sean D., et al.
Publicado: (2003)

Clathrin-mediated endocytosis in AP-2–depleted cells
por: Motley, Alison, et al.
Publicado: (2003)

The AP2 adaptor enhances clathrin coat stiffness
por: Lherbette, Michael, et al.
Publicado: (2019)

α-Synuclein Dimers Impair Vesicle Fission during Clathrin-Mediated Synaptic Vesicle Recycling
por: Medeiros, Audrey T., et al.
Publicado: (2017)

Flat clathrin lattices: stable features of the plasma membrane
por: Grove, Joe, et al.
Publicado: (2014)

AP-2-containing clathrin coats assemble on mature lysosomes
Publicado: (1996)

AP-1 and clathrin are essential for secretory granule biogenesis in Drosophila
por: Burgess, Jason, et al.
Publicado: (2011)

The Role of the Clathrin Adaptor AP-1: Polarized Sorting and Beyond
por: Nakatsu, Fubito, et al.
Publicado: (2014)

NECAPs are negative regulators of the AP2 clathrin adaptor complex
por: Beacham, Gwendolyn M, et al.
Publicado: (2018)

Clathrin-associated AP-1 controls termination of STING signalling
por: Liu, Ying, et al.
Publicado: (2022)

Clathrin-independent endocytic retrieval of SV proteins mediated by the clathrin adaptor AP-2 at mammalian central synapses
por: López-Hernández, Tania, et al.
Publicado: (2022)

Flat clathrin lattices are dynamic actin-controlled hubs for clathrin-mediated endocytosis and signalling of specific receptors
por: Leyton-Puig, Daniela, et al.
Publicado: (2017)

NOS1AP Interacts with α-Synuclein and Aggregates in Yeast and Mammalian Cells
por: Matiiv, Anton B., et al.
Publicado: (2022)

Reticular adhesions are assembled at flat clathrin lattices and opposed by active integrin α5β1
por: Hakanpää, Laura, et al.
Publicado: (2023)

Nanodissected elastically loaded clathrin lattices relax to increased curvature
por: Tagiltsev, Grigory, et al.
Publicado: (2021)

Flat clathrin lattices are linked to metastatic potential in colorectal cancer
por: Cresens, Charlotte, et al.
Publicado: (2023)

NECAP 1 Regulates AP-2 Interactions to Control Vesicle Size, Number, and Cargo During Clathrin-Mediated Endocytosis
por: Ritter, Brigitte, et al.
Publicado: (2013)

Regulation of clathrin-mediated endocytosis by hierarchical allosteric activation of AP2
por: Kadlecova, Zuzana, et al.
Publicado: (2017)

EpsinR: an AP1/clathrin interacting protein involved in vesicle trafficking
por: Mills, Ian G., et al.
Publicado: (2003)

Distribution and Function of Ap-1 Clathrin Adaptor Complexes in Polarized Epithelial Cells
por: Fölsch, Heike, et al.
Publicado: (2001)

Sorting it out: AP-2 and alternate clathrin adaptors in endocytic cargo selection
por: Traub, Linton M.
Publicado: (2003)

Differential regulation of synaptic AP-2/clathrin vesicle uncoating in synaptic plasticity
por: Candiello, Ermes, et al.
Publicado: (2017)

The AP-1A and AP-1B clathrin adaptor complexes define biochemically and functionally distinct membrane domains
por: Fölsch, Heike, et al.
Publicado: (2003)

Lattice QCD Numerical Calculation on AP1000
por: Ohta, S
Publicado: (1992)

Molecular determinants of αVβ5 localization in flat clathrin lattices – role of αVβ5 in cell adhesion and proliferation
por: Zuidema, Alba, et al.
Publicado: (2022)

Clathrin assembly protein AP-2 induces aggregation of membrane vesicles: a possible role for AP-2 in endosome formation
Publicado: (1992)

The appendage domain of the AP-2 subunit is not required for assembly or invagination of clathrin-coated pits
Publicado: (1993)

Cannot write session to /tmp/vufind_sessions/sess_9dvbohhaqnchjpt4hrea9ddgrl