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A novel phage carrying capsule depolymerase effectively relieves pneumonia caused by multidrug-resistant Klebsiella aerogenes

BACKGROUND: Klebsiella aerogenes can cause ventilator-associated pneumonia by forming biofilms, and it is frequently associated with multidrug resistance. Phages are good antibiotic alternatives with unique advantages. There has been a lack of phage therapeutic explorations, kinetic studies, and int...

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Detalles Bibliográficos
Autores principales: Cui, Xiaohu, Du, Bing, Feng, Junxia, Feng, Yanling, Fan, Zheng, Chen, Jinfeng, Cui, Jinghua, Gan, Lin, Fu, Tongtong, Tian, Ziyan, Zhang, Rui, Yan, Chao, Zhao, Hanqing, Xu, Wenjian, Xu, Ziying, Yu, Zihui, Ding, Zanbo, Li, Zhoufei, Chen, Yujie, Xue, Guanhua, Yuan, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470133/
https://www.ncbi.nlm.nih.gov/pubmed/37653407
http://dx.doi.org/10.1186/s12929-023-00946-y