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Complete fatty degeneration of thymus associates with male sex, obesity and loss of circulating naïve CD8(+) T cells in a Swedish middle-aged population

BACKGROUND: Fatty degeneration of thymus (or thymus involution) has long been considered a normal ageing process. However, there is emerging evidence that thymic involution is linked to T cell aging, chronic inflammation and increased morbidity. Other factors, aside from chronological age, have been...

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Detalles Bibliográficos
Autores principales: Sandstedt, Mårten, Chung, Rosanna W S, Skoglund, Camilla, Lundberg, Anna K., Östgren, Carl Johan, Ernerudh, Jan, Jonasson, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470174/
https://www.ncbi.nlm.nih.gov/pubmed/37653480
http://dx.doi.org/10.1186/s12979-023-00371-7