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Complete fatty degeneration of thymus associates with male sex, obesity and loss of circulating naïve CD8(+) T cells in a Swedish middle-aged population
BACKGROUND: Fatty degeneration of thymus (or thymus involution) has long been considered a normal ageing process. However, there is emerging evidence that thymic involution is linked to T cell aging, chronic inflammation and increased morbidity. Other factors, aside from chronological age, have been...
Autores principales: | Sandstedt, Mårten, Chung, Rosanna W S, Skoglund, Camilla, Lundberg, Anna K., Östgren, Carl Johan, Ernerudh, Jan, Jonasson, Lena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470174/ https://www.ncbi.nlm.nih.gov/pubmed/37653480 http://dx.doi.org/10.1186/s12979-023-00371-7 |
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