Socs1-knockout in skin-resident CD4(+) T cells in a protracted contact-allergic reaction results in an autonomous skin inflammation with features of early-stage mycosis fungoides

Recent detailed genomic analysis of mycosis fungoides (MF) identified suppressor of cytokine signaling 1 (SOCS1), an inhibitor of JAK/STAT signaling, as one of the frequently deleted tumor suppressors in MF, and one-copy deletion of SOCS1 was confirmed in early-stage MF lesions. To better understand...

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Detalles Bibliográficos
Autores principales: Luo, Yixin, Vermeer, Maarten H., de Haan, Sanne, Kinderman, Priscilla, de Gruijl, Frank R., van Hall, Thorbald, Tensen, Cornelis P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470183/
https://www.ncbi.nlm.nih.gov/pubmed/37664523
http://dx.doi.org/10.1016/j.bbrep.2023.101535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470183/
https://www.ncbi.nlm.nih.gov/pubmed/37664523
http://dx.doi.org/10.1016/j.bbrep.2023.101535

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