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PRDX1 Cys52Ser variant alleviates nonalcoholic steatohepatitis by reducing inflammation in mice

OBJECTIVE: Peroxiredoxin 1 (PRDX1) is a peroxidase and guards against oxidative stress by scavenging intracellular peroxides, whereas it also has been shown to stimulate inflammatory response by functioning as a chaperone protein. The potential in vivo link between PRDX1's peroxidase activity a...

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Detalles Bibliográficos
Autores principales: Bai, Zhonghao, Yin, Wen, Liu, Rui, Tang, Minglei, Shi, Xiaofeng, Luo, Cheng, Xie, Xiangyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470253/
https://www.ncbi.nlm.nih.gov/pubmed/37562742
http://dx.doi.org/10.1016/j.molmet.2023.101789