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PRDX1 Cys52Ser variant alleviates nonalcoholic steatohepatitis by reducing inflammation in mice
OBJECTIVE: Peroxiredoxin 1 (PRDX1) is a peroxidase and guards against oxidative stress by scavenging intracellular peroxides, whereas it also has been shown to stimulate inflammatory response by functioning as a chaperone protein. The potential in vivo link between PRDX1's peroxidase activity a...
Autores principales: | Bai, Zhonghao, Yin, Wen, Liu, Rui, Tang, Minglei, Shi, Xiaofeng, Luo, Cheng, Xie, Xiangyang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470253/ https://www.ncbi.nlm.nih.gov/pubmed/37562742 http://dx.doi.org/10.1016/j.molmet.2023.101789 |
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