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Sex disparities in non-small cell lung cancer: mechanistic insights from a cRaf transgenic disease model

BACKGROUND: Women are at greater risk of developing non-small cell lung cancer (NSCLC), yet the underlying causes remain unclear. METHODS: We performed whole genome scans in lung tumours of cRaf transgenic mice and identified miRNA, transcription factor and hormone receptor dependent gene regulation...

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Detalles Bibliográficos
Autores principales: Zhong, Shen, Borlak, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470261/
https://www.ncbi.nlm.nih.gov/pubmed/37625265
http://dx.doi.org/10.1016/j.ebiom.2023.104763