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Omega-3 fatty acid-based self-microemulsifying drug delivery system (SMEDDS) of pioglitazone: Optimization, in vitro and in vivo studies

Pioglitazone (PGL) is an effective insulin sensitizer, however, side effects such as accumulation of subcutaneous fat, edema, and weight gain as well as poor oral bioavailability limit its therapeutic potential for oral delivery. Recent studies have shown that combination of both, PGL and fish oil s...

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Detalles Bibliográficos
Autores principales: Emad, Nasr A., Sultana, Yasmin, Aqil, Mohd, Saleh, Asmaa, Al kamaly, Omkulthom, Nasr, Fahd A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470285/
https://www.ncbi.nlm.nih.gov/pubmed/37663396
http://dx.doi.org/10.1016/j.sjbs.2023.103778