Developing a peptide to disrupt cohesin head domain interactions

Cohesin mediates the 3-D structure of chromatin and is involved in maintaining genome stability and function. The cohesin core comprises Smc1 and Smc3, elongated-shaped proteins that dimerize through globular domains at their edges, called head and hinge. ATP binding to the Smc heads induces their d...

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Detalles Bibliográficos
Autores principales: Elias, Maria, Gani, Samar, Lerner, Yana, Yamin, Katreen, Tor, Chen, Patel, Adarsh, Matityahu, Avi, Dessau, Moshe, Qvit, Nir, Onn, Itay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470313/
https://www.ncbi.nlm.nih.gov/pubmed/37664609
http://dx.doi.org/10.1016/j.isci.2023.107498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470313/
https://www.ncbi.nlm.nih.gov/pubmed/37664609
http://dx.doi.org/10.1016/j.isci.2023.107498

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