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Plant flavonoid inhibition of SARS-CoV-2 main protease and viral replication

Plant-based flavonoids have been evaluated as inhibitors of β-coronavirus replication and as therapies for COVID-19 on the basis of their safety profile and widespread availability. The SARS-CoV-2 main protease (Mpro) has been implicated as a target for flavonoids in silico. Yet no comprehensive in ...

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Detalles Bibliográficos
Autores principales: Lin, Lin, Chen, Da-Yuan, Scartelli, Christina, Xie, Huanzhang, Merrill-Skoloff, Glenn, Yang, Moua, Sun, Lijun, Saeed, Mohsan, Flaumenhaft, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470319/
https://www.ncbi.nlm.nih.gov/pubmed/37664626
http://dx.doi.org/10.1016/j.isci.2023.107602