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Hematopoietic stem and progenitor cells confer cross-protective trained immunity in mouse models

Recent studies suggest that infection reprograms hematopoietic stem and progenitor cells (HSPCs) to enhance innate immune responses upon secondary infectious challenge, a process called “trained immunity.” However, the specificity and cell types responsible for this response remain poorly defined. W...

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Detalles Bibliográficos
Autores principales: Kain, Bailee N., Tran, Brandon T., Luna, Pamela N., Cao, Ruoqiong, Le, Duy T., Florez, Marcus A., Maneix, Laure, Toups, Jack D., Morales-Mantilla, Daniel E., Koh, Scott, Han, Hyojeong, Jaksik, Roman, Huang, Yun, Catic, Andre, Shaw, Chad A., King, Katherine Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470378/
https://www.ncbi.nlm.nih.gov/pubmed/37664586
http://dx.doi.org/10.1016/j.isci.2023.107596