Potent dual block to HIV-1 infection using lentiviral vectors expressing fusion inhibitor peptide mC46- and Vif-resistant APOBEC3G

Gene therapy strategies that effectively inhibit HIV-1 replication are needed to reduce the requirement for lifelong antiviral therapy and potentially achieve a functional cure. We previously designed self-activating lentiviral vectors that efficiently delivered and expressed a Vif-resistant mutant...

Descripción completa

Detalles Bibliográficos
Autores principales: Delviks-Frankenberry, Krista A., Ojha, Chet R., Hermann, Kip J., Hu, Wei-Shau, Torbett, Bruce E., Pathak, Vinay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470399/
https://www.ncbi.nlm.nih.gov/pubmed/37662965
http://dx.doi.org/10.1016/j.omtn.2023.08.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470399/
https://www.ncbi.nlm.nih.gov/pubmed/37662965
http://dx.doi.org/10.1016/j.omtn.2023.08.007

Ejemplares similares