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Mechanism of assembly of snRNP cores assisted by ICln and the SMN complex in fission yeast

The spliceosomal snRNP cores, each comprised of a snRNA and a seven-membered Sm ring (D1/D2/F/E/G/D3/B), are assembled by twelve chaperoning proteins in human. However, only six assembly-assisting proteins, ICln and the SMN complex (SMN/Gemin2/Gemin6-8), have been found in Schizosaccharomyces pombe...

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Detalles Bibliográficos
Autores principales: Hu, Yan, Hou, Yan, Zhou, Shijie, Wang, Yingzhi, Shen, Congcong, Mu, Li, Su, Dan, Zhang, Rundong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470402/
https://www.ncbi.nlm.nih.gov/pubmed/37664592
http://dx.doi.org/10.1016/j.isci.2023.107604