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A retrospective study of consistency between immunohistochemistry and polymerase chain reaction of microsatellite instability in endometrial cancer

OBJECTIVES: Identification of endometrial cancers (EC) with mismatch repair deficiency (dMMR) or microsatellite instability-high (MSI-H) is essential for Lynch syndrome screening and treatment stratification. We aimed to assess the utility of immunohistochemistry (IHC) staining for MMR protein expre...

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Detalles Bibliográficos
Autores principales: Wang, Cheng, Kuang, Wei, Zeng, Jing, Ren, Yang, Liu, Qianqi, Sun, Huanxin, Feng, Min, Liang, Dongni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470453/
https://www.ncbi.nlm.nih.gov/pubmed/37663290
http://dx.doi.org/10.7717/peerj.15920