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Altered exocytosis of inhibitory synaptic vesicles at single presynaptic terminals of cultured striatal neurons in a knock-in mouse model of Huntington’s disease

Huntington’s disease (HD) is a progressive dominantly inherited neurodegenerative disease caused by the expansion of a cytosine-adenine-guanine (CAG) trinucleotide repeat in the huntingtin gene, which encodes the mutant huntingtin protein containing an expanded polyglutamine tract. One of neuropatho...

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Detalles Bibliográficos
Autores principales: Xu, Chen, Chen, Sidong, Chen, Xingxiang, Ho, Ka Hei, Park, Chungwon, Yoo, Hanna, Lee, Suk-Ho, Park, Hyokeun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470468/
https://www.ncbi.nlm.nih.gov/pubmed/37664244
http://dx.doi.org/10.3389/fnmol.2023.1175522