Demethylation of EHMT1/GLP Protein Reprograms Its Transcriptional Activity and Promotes Prostate Cancer Progression

Epigenetic reprogramming, mediated by genomic alterations and dysregulation of histone reader and writer proteins, plays a critical role in driving prostate cancer progression and treatment resistance. However, the specific function and regulation of EHMT1 (also known as GLP) and EHMT2 (also known a...

Descripción completa

Detalles Bibliográficos
Autores principales: Besschetnova, Anna, Han, Wanting, Liu, Mingyu, Gao, Yanfei, Li, Muqing, Wang, Zifeng, Labaf, Maryam, Patalano, Susan, Venkataramani, Kavita, Muriph, Rachel E., Macoska, Jill A., Siegfried, Kellee R., Evans, Jason, Balk, Steven P., Gao, Shuai, Han, Dong, Cai, Changmeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470473/
https://www.ncbi.nlm.nih.gov/pubmed/37663929
http://dx.doi.org/10.1158/2767-9764.CRC-23-0208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470473/
https://www.ncbi.nlm.nih.gov/pubmed/37663929
http://dx.doi.org/10.1158/2767-9764.CRC-23-0208

Ejemplares similares