Demethylation of EHMT1/GLP Protein Reprograms Its Transcriptional Activity and Promotes Prostate Cancer Progression

Epigenetic reprogramming, mediated by genomic alterations and dysregulation of histone reader and writer proteins, plays a critical role in driving prostate cancer progression and treatment resistance. However, the specific function and regulation of EHMT1 (also known as GLP) and EHMT2 (also known a...

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Detalles Bibliográficos
Autores principales: Besschetnova, Anna, Han, Wanting, Liu, Mingyu, Gao, Yanfei, Li, Muqing, Wang, Zifeng, Labaf, Maryam, Patalano, Susan, Venkataramani, Kavita, Muriph, Rachel E., Macoska, Jill A., Siegfried, Kellee R., Evans, Jason, Balk, Steven P., Gao, Shuai, Han, Dong, Cai, Changmeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470473/
https://www.ncbi.nlm.nih.gov/pubmed/37663929
http://dx.doi.org/10.1158/2767-9764.CRC-23-0208

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