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SARS-CoV-2 nonstructural protein 6 from Alpha to Omicron: evolution of a transmembrane protein

We recently reported that mutations in both the spike glycoprotein and nonstructural protein 6 (nsp6) were associated with attenuation of the SARS-CoV-2 Omicron BA.1 variant. While mutations in spike allow evasion of neutralizing antibodies and promote specific modes of viral entry, the role of nsp6...

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Detalles Bibliográficos
Autores principales: Feng, Shuchen, O'Brien, Amornrat, Chen, Da-Yuan, Saeed, Mohsan, Baker, Susan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470488/
https://www.ncbi.nlm.nih.gov/pubmed/37477426
http://dx.doi.org/10.1128/mbio.00688-23