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Broad susceptibility of Candida auris strains to 8-hydroxyquinolines and mechanisms of resistance

The fungal pathogen Candida auris represents a severe threat to hospitalized patients. Its resistance to multiple classes of antifungal drugs and ability to spread and resist decontamination in healthcare settings make it especially dangerous. We screened 1,990 clinically approved and late-stage inv...

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Detalles Bibliográficos
Autores principales: Lohse, Matthew B., Laurie, Matthew T., Levan, Sophia, Ziv, Naomi, Ennis, Craig L., Nobile, Clarissa J., DeRisi, Joseph, Johnson, Alexander D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470496/
https://www.ncbi.nlm.nih.gov/pubmed/37493629
http://dx.doi.org/10.1128/mbio.01376-23