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Salmonella enterica serovar Typhi uses two type 3 secretion systems to replicate in human macrophages and colonize humanized mice

Salmonella enterica serovar Typhi (S. Typhi) is a human-restricted pathogen that replicates in macrophages. In this study, we investigated the roles of the S. Typhi type 3 secretion systems (T3SSs) encoded on Salmonella pathogenicity islands (SPI)-1 (T3SS-1) and SPI-2 (T3SS-2) during human macrophag...

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Detalles Bibliográficos
Autores principales: Hamblin, Meagan, Schade, Ruth, Narasimhan, Ramya, Monack, Denise M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470537/
https://www.ncbi.nlm.nih.gov/pubmed/37341487
http://dx.doi.org/10.1128/mbio.01137-23