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A DNA phosphorothioation-based Dnd defense system provides resistance against various phages and is compatible with the Ssp defense system
DndABCDE-catalyzed DNA phosphorothioation (PT), in which the nonbridging oxygen is swapped with a sulfur atom, was first identified in the bacterial genome. Usually, this modification gene cluster is paired with a restriction module consisting of DndF, DndG, and DndH. Although the mechanisms for the...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470545/ https://www.ncbi.nlm.nih.gov/pubmed/37260233 http://dx.doi.org/10.1128/mbio.00933-23 |