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A DNA phosphorothioation-based Dnd defense system provides resistance against various phages and is compatible with the Ssp defense system

DndABCDE-catalyzed DNA phosphorothioation (PT), in which the nonbridging oxygen is swapped with a sulfur atom, was first identified in the bacterial genome. Usually, this modification gene cluster is paired with a restriction module consisting of DndF, DndG, and DndH. Although the mechanisms for the...

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Detalles Bibliográficos
Autores principales: Jiang, Susu, Chen, Ke, Wang, Yingying, Zhang, Yueying, Tang, Yaru, Huang, Wanqiu, Xiong, Xiaolin, Chen, Shi, Chen, Chao, Wang, Lianrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470545/
https://www.ncbi.nlm.nih.gov/pubmed/37260233
http://dx.doi.org/10.1128/mbio.00933-23