Cargando…

APOBEC3 degradation is the primary function of HIV-1 Vif determining virion infectivity in the myeloid cell line THP-1

HIV-1 must overcome multiple innate antiviral mechanisms to replicate in CD4(+) T lymphocytes and macrophages. Previous studies have demonstrated that the apolipoprotein B mRNA editing enzyme polypeptide-like 3 (APOBEC3, A3) family of proteins (at least A3D, A3F, A3G, and stable A3H haplotypes) cont...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ikeda, Terumasa, Shimizu, Ryo, Nasser, Hesham, Carpenter, Michael A., Cheng, Adam Z., Brown, William L., Sauter, Daniel, Harris, Reuben S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470580/ https://www.ncbi.nlm.nih.gov/pubmed/37555667 http://dx.doi.org/10.1128/mbio.00782-23

Ejemplares similares

APOBEC3 degradation is the primary function of HIV-1 Vif for virus replication in the myeloid cell line THP-1
por: Ikeda, Terumasa, et al.
Publicado: (2023)

Potential Utilization of APOBEC3-Mediated Mutagenesis for an HIV-1 Functional Cure
por: Ikeda, Terumasa, et al.
Publicado: (2021)

Small molecules that inhibit Vif-induced degradation of APOBEC3G
por: Matsui, Masashi, et al.
Publicado: (2014)

Degradation of the cancer genomic DNA deaminase APOBEC3B by SIV Vif
por: Land, Allison M., et al.
Publicado: (2015)

Dual Functionality of HIV-1 Vif in APOBEC3 Counteraction and Cell Cycle Arrest
por: Salamango, Daniel J., et al.
Publicado: (2021)

HIV-1 Vif, APOBEC, and Intrinsic Immunity
por: Goila-Gaur, Ritu, et al.
Publicado: (2008)

Degradation-Independent Inhibition of APOBEC3G by the HIV-1 Vif Protein
por: Stupfler, Benjamin, et al.
Publicado: (2021)

The dimerization domain of HIV-1 viral infectivity factor Vif is required to block virion incorporation of APOBEC3G
por: Miller, James H, et al.
Publicado: (2007)

Natural Polymorphisms in Human APOBEC3H and HIV-1 Vif Combine in Primary T Lymphocytes to Affect Viral G-to-A Mutation Levels and Infectivity
por: Refsland, Eric W., et al.
Publicado: (2014)

Structure of the Vif-binding domain of the antiviral enzyme APOBEC3G
por: Kouno, Takahide, et al.
Publicado: (2015)

Suppression of APOBEC3-mediated restriction of HIV-1 by Vif
por: Feng, Yuqing, et al.
Publicado: (2014)

Evolutionary Paradigms from Ancient and Ongoing Conflicts between the Lentiviral Vif Protein and Mammalian APOBEC3 Enzymes
por: Harris, Reuben S., et al.
Publicado: (2016)

HIV-1 Vif Triggers Cell Cycle Arrest by Degrading Cellular PPP2R5 Phospho-regulators
por: Salamango, Daniel J., et al.
Publicado: (2019)

The HDAC6/APOBEC3G complex regulates HIV-1 infectiveness by inducing Vif autophagic degradation
por: Valera, María-Soledad, et al.
Publicado: (2015)

HIV-1 Vif and APOBEC3G: Multiple roads to one goal
por: Goncalves, Joao, et al.
Publicado: (2004)

Structural basis of antagonism of human APOBEC3F by HIV-1 Vif
por: Hu, Yingxia, et al.
Publicado: (2019)

The structural basis for HIV-1 Vif antagonism of human APOBEC3G
por: Li, Yen-Li, et al.
Publicado: (2023)

Species‐specific differences in the ability of feline lentiviral Vif to degrade feline APOBEC3 proteins
por: Yoshikawa, Rokusuke, et al.
Publicado: (2016)

ASK1 restores the antiviral activity of APOBEC3G by disrupting HIV-1 Vif-mediated counteraction
por: Miyakawa, Kei, et al.
Publicado: (2015)

Host Restriction of Lentiviruses and Viral Countermeasures: APOBEC3 and Vif
por: Jónsson, Stefán R., et al.
Publicado: (2013)

Structural determinants of HIV-1 Vif susceptibility and DNA binding in APOBEC3F
por: Siu, Karen K., et al.
Publicado: (2013)

Opossum APOBEC1 is a DNA mutator with retrovirus and retroelement restriction activity
por: Ikeda, Terumasa, et al.
Publicado: (2017)

Stability of APOBEC3F in the Presence of the APOBEC3 Antagonist HIV-1 Vif Increases at the Expense of Co-Expressed APOBEC3H Haplotype I
por: Yousefi, Maria, et al.
Publicado: (2023)

HIV-1 Vif binds to APOBEC3G mRNA and inhibits its translation
por: Mercenne, Gaëlle, et al.
Publicado: (2010)

Identification of HIV-1 Vif Regions Required for CBF-β Interaction and APOBEC3 Suppression
por: Wang, Hong, et al.
Publicado: (2014)

Development of Lentiviral Vectors for HIV-1 Gene Therapy with Vif-Resistant APOBEC3G
por: Delviks-Frankenberry, Krista A., et al.
Publicado: (2019)

Natural APOBEC3C variants can elicit differential HIV-1 restriction activity
por: Anderson, Brett D., et al.
Publicado: (2018)

HIV-1 adaptation studies reveal a novel Env-mediated homeostasis mechanism for evading lethal hypermutation by APOBEC3G
por: Ikeda, Terumasa, et al.
Publicado: (2018)

Towards Inhibition of Vif-APOBEC3G Interaction: Which Protein to Target?
por: Cadima-Couto, Iris, et al.
Publicado: (2010)

Determinants of FIV and HIV Vif sensitivity of feline APOBEC3 restriction factors
por: Zhang, Zeli, et al.
Publicado: (2016)

Cyclin F/FBXO1 Interacts with HIV-1 Viral Infectivity Factor (Vif) and Restricts Progeny Virion Infectivity by Ubiquitination and Proteasomal Degradation of Vif Protein through SCF(cyclin F) E3 Ligase Machinery
por: Augustine, Tracy, et al.
Publicado: (2017)

Paradigm development: Comparative and predictive 3D modeling of HIV-1 Virion Infectivity Factor (vif)
por: Balaji, Seetharaaman, et al.
Publicado: (2006)

Definition of the interacting interfaces of Apobec3G and HIV-1 Vif using MAPPIT mutagenesis analysis
por: Lavens, Delphine, et al.
Publicado: (2010)

Definition of the interacting interfaces of Apobec3G and HIV-1 Vif using MAPPIT mutagenesis analysis
por: Lavens, Delphine, et al.
Publicado: (2010)

HIV-1 Vif N-terminal Motif is required for recruitment of Cul5 to Suppress APOBEC3
por: Evans, Sean L, et al.
Publicado: (2014)

Structural insights into RNA bridging between HIV-1 Vif and antiviral factor APOBEC3G
por: Kouno, Takahide, et al.
Publicado: (2023)

APOBEC3G encapsidation into HIV-1 virions: which RNA is it?
por: Strebel, Klaus, et al.
Publicado: (2008)

Genetic and functional characterization of HIV-1 Vif on APOBEC3G degradation: First report of emergence of B/C recombinants from North India
por: Ronsard, Larance, et al.
Publicado: (2015)

Host AKT-mediated phosphorylation of HIV-1 accessory protein Vif potentiates infectivity via enhanced degradation of the restriction factor APOBEC3G
por: Raja, Rameez, et al.
Publicado: (2022)

Structural basis of HIV-1 Vif-mediated E3 ligase targeting of host APOBEC3H
por: Ito, Fumiaki, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_1vckoif13mp3e24uu9irkheb04