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Impact of HIV-1 Vpu-mediated downregulation of CD48 on NK-cell-mediated antibody-dependent cellular cytotoxicity
HIV-1 evades antibody-dependent cellular cytotoxicity (ADCC) responses not only by controlling Env conformation and quantity at the cell surface but also by altering NK cell activation via the downmodulation of several ligands of activating and co-activating NK cell receptors. The signaling lymphocy...
Autores principales: | Marchitto, Lorie, Benlarbi, Mehdi, Prévost, Jérémie, Laumaea, Annemarie, Descôteaux-Dinelle, Jade, Medjahed, Halima, Bourassa, Catherine, Gendron-Lepage, Gabrielle, Kirchhoff, Frank, Sauter, Daniel, Hahn, Beatrice H., Finzi, Andrés, Richard, Jonathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470595/ https://www.ncbi.nlm.nih.gov/pubmed/37404017 http://dx.doi.org/10.1128/mbio.00789-23 |
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