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Zika virus dumbbell-1 structure is critical for sfRNA presence and cytopathic effect during infection

All flaviviruses contain conserved RNA structures in the 3′ untranslated region (3′ UTR) that are important for flavivirus RNA replication, translation, and pathogenesis. Flaviviruses like Zika virus (ZIKV) contain multiple conserved RNA structures in the viral 3′ UTR, including the structure known...

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Detalles Bibliográficos
Autores principales: Graham, Monica E., Merrick, Camille, Akiyama, Benjamin M., Szucs, Matthew J., Leach, Sarah, Kieft, Jeffery S., Beckham, J. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470596/
https://www.ncbi.nlm.nih.gov/pubmed/37417764
http://dx.doi.org/10.1128/mbio.01108-23