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Integrated transcriptomics, proteomics and metabolomics-based analysis uncover TAM2-associated glycolysis and pyruvate metabolic remodeling in pancreatic cancer

INTRODUCTION: Tumor-associated macrophage 2 (TAM2) abundantly infiltrates pancreatic ductal adenocarcinoma (PAAD), and its interaction with malignant cells is involved in the regulation of tumor metabolism. In this study, we explored the metabolic heterogeneity involved in TAM2 by constructing TAM2-...

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Detalles Bibliográficos
Autores principales: Li, Xin, Du, Yan, Jiang, Wenkai, Dong, Shi, Li, Wancheng, Tang, Huan, Yi, Jianfeng, Zhou, Wence, Zhang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470650/
https://www.ncbi.nlm.nih.gov/pubmed/37662928
http://dx.doi.org/10.3389/fimmu.2023.1170223