Structural disruption of Ntox15 nuclease effector domains by immunity proteins protects against type VI secretion system intoxication in Bacteroidales

Bacteroidales use type VI secretion systems (T6SS) to competitively colonize and persist in the colon. We identify a horizontally transferred T6SS with Ntox15 family nuclease effector (Tde1) that mediates interbacterial antagonism among Bacteroidales, including several derived from a single human do...

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Detalles Bibliográficos
Autores principales: Bosch, Dustin E., Abbasian, Romina, Parajuli, Bishal, Peterson, S. Brook, Mougous, Joseph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470768/
https://www.ncbi.nlm.nih.gov/pubmed/37345922
http://dx.doi.org/10.1128/mbio.01039-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470768/
https://www.ncbi.nlm.nih.gov/pubmed/37345922
http://dx.doi.org/10.1128/mbio.01039-23

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