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Structural disruption of Ntox15 nuclease effector domains by immunity proteins protects against type VI secretion system intoxication in Bacteroidales
Bacteroidales use type VI secretion systems (T6SS) to competitively colonize and persist in the colon. We identify a horizontally transferred T6SS with Ntox15 family nuclease effector (Tde1) that mediates interbacterial antagonism among Bacteroidales, including several derived from a single human do...
Autores principales: | Bosch, Dustin E., Abbasian, Romina, Parajuli, Bishal, Peterson, S. Brook, Mougous, Joseph D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470768/ https://www.ncbi.nlm.nih.gov/pubmed/37345922 http://dx.doi.org/10.1128/mbio.01039-23 |
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