Mus musculus papillomavirus 1 E8^E2 represses expression of late protein E4 in basal-like keratinocytes via NCoR/SMRT-HDAC3 co-repressor complexes to enable wart formation in vivo

High-risk human papillomaviruses (PV) account for approximately 600,000 new cancers per year. The early protein E8^E2 is a conserved repressor of PV replication, whereas E4 is a late protein that arrests cells in G2 and collapses keratin filaments to facilitate virion release. While inactivation of...

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Detalles Bibliográficos
Autores principales: Kuehner, Franziska, Wong, Margaret, Straub, Elke, Doorbar, John, Iftner, Thomas, Roden, Richard B. S., Stubenrauch, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470772/
https://www.ncbi.nlm.nih.gov/pubmed/37382436
http://dx.doi.org/10.1128/mbio.00696-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470772/
https://www.ncbi.nlm.nih.gov/pubmed/37382436
http://dx.doi.org/10.1128/mbio.00696-23

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