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Mus musculus papillomavirus 1 E8^E2 represses expression of late protein E4 in basal-like keratinocytes via NCoR/SMRT-HDAC3 co-repressor complexes to enable wart formation in vivo
High-risk human papillomaviruses (PV) account for approximately 600,000 new cancers per year. The early protein E8^E2 is a conserved repressor of PV replication, whereas E4 is a late protein that arrests cells in G2 and collapses keratin filaments to facilitate virion release. While inactivation of...
Autores principales: | Kuehner, Franziska, Wong, Margaret, Straub, Elke, Doorbar, John, Iftner, Thomas, Roden, Richard B. S., Stubenrauch, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470772/ https://www.ncbi.nlm.nih.gov/pubmed/37382436 http://dx.doi.org/10.1128/mbio.00696-23 |
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